Cargando…
Conditions Conducive to the Glutathionylation of Complex I Subunit NDUFS1 Augment ROS Production following the Oxidation of Ubiquinone Linked Substrates, Glycerol-3-Phosphate and Proline
Mitochondrial complex I can produce large quantities of reactive oxygen species (ROS) by reverse electron transfer (RET) from the ubiquinone (UQ) pool. Glutathionylation of complex I does induce increased mitochondrial superoxide/hydrogen peroxide (O(2)(●−)/H(2)O(2)) production, but the source of th...
Autores principales: | Wang, Kevin, Hirschenson, Jonathan, Moore, Amanda, Mailloux, Ryan J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9598259/ https://www.ncbi.nlm.nih.gov/pubmed/36290766 http://dx.doi.org/10.3390/antiox11102043 |
Ejemplares similares
-
S-glutathionylation reactions in mitochondrial function and disease
por: Mailloux, Ryan J., et al.
Publicado: (2014) -
Regulation of Mitochondrial Hydrogen Peroxide Availability by Protein S-glutathionylation
por: Mailloux, Ryan J., et al.
Publicado: (2022) -
Neutrophil HIF-1α stabilization is augmented by mitochondrial ROS produced via the glycerol 3-phosphate shuttle
por: Willson, Joseph A., et al.
Publicado: (2022) -
Higher NADH Dehydrogenase [Ubiquinone] Iron–Sulfur Protein 8 (NDUFS8) Serum Levels Correlate with Better Insulin Sensitivity in Type 1 Diabetes
por: Flotyńska, Justyna, et al.
Publicado: (2022) -
Protein S-glutathionylation reactions as a global inhibitor of cell metabolism for the desensitization of hydrogen peroxide signals
por: Mailloux, Ryan J.
Publicado: (2020)