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Guanidinylated Polymyxins as Outer Membrane Permeabilizers Capable of Potentiating Rifampicin, Erythromycin, Ceftazidime and Aztreonam against Gram-Negative Bacteria

Polymyxins are considered a last-line treatment against infections caused by multidrug-resistant (MDR) Gram-negative bacteria. In addition to their use as a potent antibiotic, polymyxins have also been utilized as outer membrane (OM) permeabilizers, capable of augmenting the activity of a partner an...

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Detalles Bibliográficos
Autores principales: Ramirez, Danzel Marie, Ramirez, Danyel, Arthur, Gilbert, Zhanel, George, Schweizer, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9598282/
https://www.ncbi.nlm.nih.gov/pubmed/36289935
http://dx.doi.org/10.3390/antibiotics11101277