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Guanidinylated Polymyxins as Outer Membrane Permeabilizers Capable of Potentiating Rifampicin, Erythromycin, Ceftazidime and Aztreonam against Gram-Negative Bacteria
Polymyxins are considered a last-line treatment against infections caused by multidrug-resistant (MDR) Gram-negative bacteria. In addition to their use as a potent antibiotic, polymyxins have also been utilized as outer membrane (OM) permeabilizers, capable of augmenting the activity of a partner an...
Autores principales: | Ramirez, Danzel Marie, Ramirez, Danyel, Arthur, Gilbert, Zhanel, George, Schweizer, Frank |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9598282/ https://www.ncbi.nlm.nih.gov/pubmed/36289935 http://dx.doi.org/10.3390/antibiotics11101277 |
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