Dimethyl Fumarate Triggers the Antioxidant Defense System in Human Retinal Endothelial Cells through Nrf2 Activation

Dimethyl fumarate (DMF) is a well-known activator of Nrf2 (NF-E2-related factor 2), used in the treatment of psoriasis and multiple sclerosis. The mechanism of action consists in the modification of the cysteine residues on the Nrf2-inhibitor Keap1, thus leading to the dissociation of these two prot...

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Detalles Bibliográficos
Autores principales: Manai, Federico, Amadio, Marialaura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9598343/
https://www.ncbi.nlm.nih.gov/pubmed/36290650
http://dx.doi.org/10.3390/antiox11101924

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9598343/
https://www.ncbi.nlm.nih.gov/pubmed/36290650
http://dx.doi.org/10.3390/antiox11101924

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