Sphingosine-1-Phosphate Alleviates Irradiation Induced Salivary Gland Hypofunction through Preserving Endothelial Cells and Resident Macrophages

Radiotherapy for head-and-neck cancers frequently causes long-term hypofunction of salivary glands that severely compromises quality of life and is difficult to treat. Here, we studied effects and mechanisms of Sphingosine-1-phosphate (S1P), a versatile signaling sphingolipid, in preventing irrevers...

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Detalles Bibliográficos
Autores principales: Yang, Tao, Zhao, Qingguo, Hu, Meijun, Pan, Simin, Zhang, Linying, Zhu, Ruoxi, Zhou, Bowen, Feng, Xuanhe, Gao, Zhenhua, Zhu, Zhao, Zhang, Yu, Hu, Liang, Liu, Fei, Shan, Zhaochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9598384/
https://www.ncbi.nlm.nih.gov/pubmed/36290773
http://dx.doi.org/10.3390/antiox11102050

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9598384/
https://www.ncbi.nlm.nih.gov/pubmed/36290773
http://dx.doi.org/10.3390/antiox11102050

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