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Apical Medium Flow Influences the Morphology and Physiology of Human Proximal Tubular Cells in a Microphysiological System

There is a lack of physiologically relevant in vitro human kidney models for disease modelling and detecting drug-induced effects given the limited choice of cells and difficulty implementing quasi-physiological culture conditions. We investigated the influence of fluid shear stress on primary human...

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Detalles Bibliográficos
Autores principales: Specioso, Gabriele, Bovard, David, Zanetti, Filippo, Maranzano, Fabio, Merg, Céline, Sandoz, Antonin, Titz, Bjoern, Dalcanale, Federico, Hoeng, Julia, Renggli, Kasper, Suter-Dick, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9598399/
https://www.ncbi.nlm.nih.gov/pubmed/36290484
http://dx.doi.org/10.3390/bioengineering9100516