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Identification of Cytoprotective Small-Molecule Inducers of Heme-Oxygenase-1

Acute kidney injury (AKI) is a major public health concern with significant morbidity and mortality and no current treatments beyond supportive care and dialysis. Preclinical studies have suggested that heme-oxygenase-1 (HO-1), an enzyme that catalyzes the breakdown of heme, has promise as a potenti...

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Detalles Bibliográficos
Autores principales: Ghajar-Rahimi, Gelare, Traylor, Amie M., Mathew, Bini, Bostwick, James R., Nebane, N Miranda, Zmijewska, Anna A., Esman, Stephanie K., Thukral, Saakshi, Zhai, Ling, Sambandam, Vijaya, Cowell, Rita M., Suto, Mark J., George, James F., Augelli-Szafran, Corinne E., Agarwal, Anupam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9598442/
https://www.ncbi.nlm.nih.gov/pubmed/36290611
http://dx.doi.org/10.3390/antiox11101888