Targeting NRF2 Sensitizes Esophageal Adenocarcinoma Cells to Cisplatin through Induction of Ferroptosis and Apoptosis

Esophageal adenocarcinoma (EAC), the predominant type of esophageal cancer in the United States, develops through Barrett’s esophagus (BE)-dysplasia-carcinoma cascade. Gastroesophageal reflux disease, where acidic bile salts refluxate into the esophagus, is the main risk factor for the development o...

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Detalles Bibliográficos
Autores principales: Ballout, Farah, Lu, Heng, Chen, Zheng, Hu, Tianling, Chen, Lei, Washington, Mary Kay, El-Rifai, Wael, Peng, Dunfa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9598457/
https://www.ncbi.nlm.nih.gov/pubmed/36290582
http://dx.doi.org/10.3390/antiox11101859

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9598457/
https://www.ncbi.nlm.nih.gov/pubmed/36290582
http://dx.doi.org/10.3390/antiox11101859

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