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Targeting NRF2 Sensitizes Esophageal Adenocarcinoma Cells to Cisplatin through Induction of Ferroptosis and Apoptosis
Esophageal adenocarcinoma (EAC), the predominant type of esophageal cancer in the United States, develops through Barrett’s esophagus (BE)-dysplasia-carcinoma cascade. Gastroesophageal reflux disease, where acidic bile salts refluxate into the esophagus, is the main risk factor for the development o...
Autores principales: | Ballout, Farah, Lu, Heng, Chen, Zheng, Hu, Tianling, Chen, Lei, Washington, Mary Kay, El-Rifai, Wael, Peng, Dunfa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9598457/ https://www.ncbi.nlm.nih.gov/pubmed/36290582 http://dx.doi.org/10.3390/antiox11101859 |
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