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Depletion of CD4 and CD8 T Cells Reduces Acute Disease and Is Not Associated with Hearing Loss in ML29-Infected STAT1-/- Mice

Lassa virus (LASV) is a zoonotic virus endemic to western Africa that can cause a potentially lethal and hemorrhagic disease, Lassa fever (LF). Survivors suffer a myriad of sequelae, most notably sudden onset sensorineural hearing loss (SNHL), the mechanism of which remains unclear. Unfortunately, s...

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Detalles Bibliográficos
Autores principales: Reyna, Rachel A., Maruyama, Junki, Mantlo, Emily K., Manning, John T., Taniguchi, Satoshi, Makishima, Tomoko, Lukashevich, Igor S., Paessler, Slobodan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9598517/
https://www.ncbi.nlm.nih.gov/pubmed/36289695
http://dx.doi.org/10.3390/biomedicines10102433