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Gram-Scale Preparation of Cannflavin A from Hemp (Cannabis sativa L.) and Its Inhibitory Effect on Tryptophan Catabolism Enzyme Kynurenine-3-Monooxygenase

SIMPLE SUMMARY: Kynurenine-3-monooxygenase (KMO) is an enzyme in the neurotoxic branch of the kynurenine pathway (KP) and is a target of inhibitors with therapeutic potential against neuroinflammatory and neurodegenerative diseases. Phytochemicals from hemp (Cannabis sativa L.) including phytocannab...

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Detalles Bibliográficos
Autores principales: Puopolo, Tess, Chang, Tanran, Liu, Chang, Li, Huifang, Liu, Xu, Wu, Xian, Ma, Hang, Seeram, Navindra P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9598531/
https://www.ncbi.nlm.nih.gov/pubmed/36290320
http://dx.doi.org/10.3390/biology11101416