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Keratin Promotes Differentiation of Keratinocytes Seeded on Collagen/Keratin Hydrogels

Keratinocytes undergo a complex process of differentiation to form the stratified stratum corneum layer of the skin. In most biomimetic skin models, a 3D hydrogel fabricated out of collagen type I is used to mimic human skin. However, native skin also contains keratin, which makes up 90% of the epid...

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Detalles Bibliográficos
Autores principales: Zuniga, Kameel, Ghousifam, Neda, Sansalone, John, Senecal, Kris, Van Dyke, Mark, Rylander, Marissa Nichole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9598618/
https://www.ncbi.nlm.nih.gov/pubmed/36290526
http://dx.doi.org/10.3390/bioengineering9100559