Peroxiredoxin 2 Ameliorates AβO-Mediated Autophagy by Inhibiting ROS via the ROS–NRF2–p62 Pathway in N2a-APP Swedish Cells

In Alzheimer’s disease, reactive oxygen species (ROS) are generated by the deposition of amyloid-beta oligomers (AβOs), which represent one of the important causes of neuronal cell death. Additionally, AβOs are known to induce autophagy via ROS induction. Previous studies have shown that autophagy u...

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Detalles Bibliográficos
Autores principales: Jin, Wei, Kam, Min Kyoung, Lee, Sung Woo, Park, Young-Ho, Lee, Hong Jun, Lee, Dong-Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9598687/
https://www.ncbi.nlm.nih.gov/pubmed/36290612
http://dx.doi.org/10.3390/antiox11101889

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9598687/
https://www.ncbi.nlm.nih.gov/pubmed/36290612
http://dx.doi.org/10.3390/antiox11101889

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