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Peroxiredoxin 2 Ameliorates AβO-Mediated Autophagy by Inhibiting ROS via the ROS–NRF2–p62 Pathway in N2a-APP Swedish Cells
In Alzheimer’s disease, reactive oxygen species (ROS) are generated by the deposition of amyloid-beta oligomers (AβOs), which represent one of the important causes of neuronal cell death. Additionally, AβOs are known to induce autophagy via ROS induction. Previous studies have shown that autophagy u...
Autores principales: | Jin, Wei, Kam, Min Kyoung, Lee, Sung Woo, Park, Young-Ho, Lee, Hong Jun, Lee, Dong-Seok |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9598687/ https://www.ncbi.nlm.nih.gov/pubmed/36290612 http://dx.doi.org/10.3390/antiox11101889 |
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