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Critical Sites on Ostreolysin Are Responsible for Interaction with Cytoskeletal Proteins

We explored the structural features of recombinant ostreolysin A (rOlyA), a protein produced by Pleurotus ostreatus and responsible for binding to α/β-tubulin. We found that rOlyA cell internalization is essential for the induction of adipocyte-associated activity, which is mediated by the interacti...

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Detalles Bibliográficos
Autores principales: Berke, Nastacia Adler, Di Pizio, Antonella, Vaden, Timothy D., Shoval, Irit, Gover, Ofer, Waiger, Daniel, Solomon, Gili, Sepčić, Kristina, Schwartz, Betty
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9598724/
https://www.ncbi.nlm.nih.gov/pubmed/36289704
http://dx.doi.org/10.3390/biomedicines10102442