WDR73 Depletion Destabilizes PIP4K2C Activity and Impairs Focal Adhesion Formation in Galloway–Mowat Syndrome

SIMPLE SUMMARY: Galloway–Mowat syndrome is a rare genetic disease, classically characterized by a combination of various neurological symptoms and nephrotic syndrome. WDR73 is the pathogenic gene responsible for Galloway–Mowat syndrome. However, the pathological and molecular mechanisms of Galloway–...

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Detalles Bibliográficos
Autores principales: Li, Hongyan, Liu, Fang, Kuang, Hanzhe, Teng, Hua, Chen, Siyi, Zeng, Sijing, Zhou, Qimin, Li, Zhaokai, Liang, Desheng, Li, Zhuo, Wu, Lingqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9598763/
https://www.ncbi.nlm.nih.gov/pubmed/36290302
http://dx.doi.org/10.3390/biology11101397

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9598763/
https://www.ncbi.nlm.nih.gov/pubmed/36290302
http://dx.doi.org/10.3390/biology11101397

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