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Co-Expression of Pig IL-2 and Fusion Bovine Cathelicidin Gene by Recombinant Plasmids in Yeast and Their Promotion of Mouse Antibacterial Defense

SIMPLE SUMMARY: 1. Oral inoculation with recombinant yeast co-expressing pig IL-2 and fused bovine cathelicidin (FBC) significantly enhanced systemic immunity in mice. 2. The inoculated mice displayed stronger resistance against E. coli or S. aureus infection. 3. Recombinant yeast co-expressing PIL-...

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Detalles Bibliográficos
Autores principales: Chen, Jianlin, Peng, Junjie, Ma, Changjun, Zhang, Linhan, Wu, Xueyin, Wei, Hong, Li, Jianglin, Lü, Xuebin, Gao, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9598770/
https://www.ncbi.nlm.nih.gov/pubmed/36290395
http://dx.doi.org/10.3390/biology11101491