Prevention of Testicular Damage by Indole Derivative MMINA via Upregulated StAR and CatSper Channels with Coincident Suppression of Oxidative Stress and Inflammation: In Silico and In Vivo Validation

Cis-diamminedichloroplatinum (II) (CDDP) is a widely used antineoplastic agent with numerous associated side effects. We investigated the mechanisms of action of the indole derivative N’-(4-dimethylaminobenzylidene)-2-1-(4-(methylsulfinyl) benzylidene)-5-fluoro-2-methyl-1H-inden-3-yl) acetohydrazide...

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Detalles Bibliográficos
Autores principales: Afsar, Tayyaba, Razak, Suhail, Trembley, Janeen H., Khan, Khushbukhat, Shabbir, Maria, Almajwal, Ali, Alruwaili, Nawaf W., Ijaz, Muhammad Umar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9598787/
https://www.ncbi.nlm.nih.gov/pubmed/36290786
http://dx.doi.org/10.3390/antiox11102063

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9598787/
https://www.ncbi.nlm.nih.gov/pubmed/36290786
http://dx.doi.org/10.3390/antiox11102063

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