Genistein Restricts the Epithelial Mesenchymal Transformation (EMT) and Stemness of Hepatocellular Carcinoma via Upregulating miR-1275 to Inhibit the EIF5A2/PI3K/Akt Pathway

SIMPLE SUMMARY: Genistein is a natural phytoestrogen with various antitumor effects. Our study focused on exploring the mechanisms of microRNAs and genistein to inhibit the epithelial mesenchymal transformation (EMT) and stemness of hepatocellular carcinoma (HCC). We found that miR-1275 was more hig...

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Detalles Bibliográficos
Autores principales: Yang, Xiao, Jiang, Wangjie, Kong, Xiangxu, Zhou, Xiao, Zhu, Deming, Kong, Lianbao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9598820/
https://www.ncbi.nlm.nih.gov/pubmed/36290289
http://dx.doi.org/10.3390/biology11101383

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9598820/
https://www.ncbi.nlm.nih.gov/pubmed/36290289
http://dx.doi.org/10.3390/biology11101383

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