Sp1-Mediated Prdx6 Upregulation Leads to Clasmatodendrosis by Increasing Its aiPLA2 Activity in the CA1 Astrocytes in Chronic Epilepsy Rats

Clasmatodendrosis is an autophagic astroglial degeneration (a non-apoptotic (type II) programmed cell death) whose underlying mechanisms are fully understood. Peroxiredoxin-6 (Prdx6), the “non-selenium glutathione peroxidase (NSGPx)”, is the only member of the 1-cysteine peroxiredoxin family. Unlike...

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Detalles Bibliográficos
Autores principales: Kim, Ji-Eun, Lee, Duk-Shin, Kang, Tae-Cheon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9598987/
https://www.ncbi.nlm.nih.gov/pubmed/36290607
http://dx.doi.org/10.3390/antiox11101883

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9598987/
https://www.ncbi.nlm.nih.gov/pubmed/36290607
http://dx.doi.org/10.3390/antiox11101883

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