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Volumetric Analysis of Glioblastoma for Determining Which CpG Sites Should Be Tested by Pyrosequencing to Predict Temozolomide Efficacy

The aim of the present study was to determine which individual or combined CpG sites among O(6)-methylguanine DNA methyltransferase CpG 74–89 in glioblastoma mainly affects the response to temozolomide resulting from CpG methylation using statistical analyses focused on the tumor volume ratio (TVR)....

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Detalles Bibliográficos
Autores principales: Hosoya, Tomohiro, Takahashi, Masamichi, Davey, Calvin, Sese, Jun, Honda-Kitahara, Mai, Miyakita, Yasuji, Ohno, Makoto, Yanagisawa, Shunsuke, Omura, Takaki, Kawauchi, Daisuke, Ozeki, Yukie, Kikuchi, Miyu, Nakano, Tomoyuki, Yoshida, Akihiko, Igaki, Hiroshi, Matsushita, Yuko, Ichimura, Koichi, Narita, Yoshitaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599060/
https://www.ncbi.nlm.nih.gov/pubmed/36291588
http://dx.doi.org/10.3390/biom12101379