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Galectin-3 Is a Natural Binding Ligand of MCAM (CD146, MUC18) in Melanoma Cells and Their Interaction Promotes Melanoma Progression

Melanoma cell adhesion molecule (MCAM, CD146, MUC18) is a heavily glycosylated transmembrane protein and a marker of melanoma metastasis. It is expressed in advanced primary melanoma and metastasis but rarely in benign naevi or normal melanocytes. More and more evidence has shown that activation of...

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Detalles Bibliográficos
Autores principales: Pang, Yaoyu, Maxwell, Ellen, Sindrewicz-Goral, Paulina, Shapanis, Andrew, Li, Shun, Morgan, Mark, Yu, Lu-Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599063/
https://www.ncbi.nlm.nih.gov/pubmed/36291660
http://dx.doi.org/10.3390/biom12101451