Statins Alleviate Tumor Hypoxia in Prostate Cancer Models by Decreasing Oxygen Consumption: An Opportunity for Radiosensitization?

Background: Because statins were found to decrease the oxygen consumption rate (OCR) of a variety of normal cells, our hypothesis was that statins may also decrease the OCR of cancer cells, alleviate tumor hypoxia and radiosensitize tumors. Methods: OCR was assessed using the Seahorse XF96 technolog...

Descripción completa

Detalles Bibliográficos
Autores principales: d’Hose, Donatienne, Mignion, Lionel, Hamelin, Loïc, Sonveaux, Pierre, Jordan, Bénédicte F., Gallez, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599109/
https://www.ncbi.nlm.nih.gov/pubmed/36291627
http://dx.doi.org/10.3390/biom12101418

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599109/
https://www.ncbi.nlm.nih.gov/pubmed/36291627
http://dx.doi.org/10.3390/biom12101418

Ejemplares similares