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Human Alpha 1 Antitrypsin Suppresses NF-κB Activity and Extends Lifespan in Adult Drosophila

Human alpha 1 antitrypsin (hAAT) is a multifunctional protein that has been shown to have anti-inflammatory and cellular protective properties. While previous studies demonstrated the antiaging potential of hAAT, the mechanism(s) underlying the antiaging effect remain elusive. In this study, we perf...

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Detalles Bibliográficos
Autores principales: Yuan, Ye, Van Belkum, Max, O’Brien, Alana, Garcia, Alain, Troncoso, Karla, Elshikha, Ahmed S., Zhou, Lei, Song, Sihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599126/
https://www.ncbi.nlm.nih.gov/pubmed/36291555
http://dx.doi.org/10.3390/biom12101347