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Increased Extrasynaptic Glutamate Escape in Stochastically Shaped Probabilistic Synaptic Environment

Excitatory synapses in the brain are often surrounded by nanoscopic astroglial processes that express high-affinity glutamate transporters at a high surface density. This ensures that the bulk of glutamate leaving the synaptic cleft is taken up for its subsequent metabolic conversion and replenishme...

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Detalles Bibliográficos
Autores principales: Savtchenko, Leonid P., Rusakov, Dmitri A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599130/
https://www.ncbi.nlm.nih.gov/pubmed/36289667
http://dx.doi.org/10.3390/biomedicines10102406