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Prevention and Therapy of Metastatic HER-2(+) Mammary Carcinoma with a Human Candidate HER-2 Virus-like Particle Vaccine

Vaccines are a promising therapeutic alternative to monoclonal antibodies against HER-2(+) breast cancer. We present the preclinical activity of an ES2B-C001, a VLP-based vaccine being developed for human breast cancer therapy. FVB mice challenged with HER-2(+) mammary carcinoma cells QD developed p...

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Detalles Bibliográficos
Autores principales: Ruzzi, Francesca, Palladini, Arianna, Clemmensen, Stine, Strøbæk, Anette, Buijs, Nicolaas, Domeyer, Tanja, Dorosz, Jerzy, Soroka, Vladislav, Grzadziela, Dagmara, Rasmussen, Christina Jo, Nielsen, Ida Busch, Soegaard, Max, Semprini, Maria Sofia, Scalambra, Laura, Angelicola, Stefania, Landuzzi, Lorena, Lollini, Pier-Luigi, Thorn, Mette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599132/
https://www.ncbi.nlm.nih.gov/pubmed/36289916
http://dx.doi.org/10.3390/biomedicines10102654