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High-Resolution Ribosome Profiling Reveals Gene-Specific Details of UGA Re-Coding in Selenoprotein Biosynthesis

Co-translational incorporation of selenocysteine (Sec) into selenoproteins occurs at UGA codons in a process in which translational elongation competes with translational termination. Selenocysteine insertion sequence-binding protein 2 (SECISBP2) greatly enhances Sec incorporation into selenoprotein...

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Detalles Bibliográficos
Autores principales: Bohleber, Simon, Fradejas-Villar, Noelia, Zhao, Wenchao, Reuter, Uschi, Schweizer, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599142/
https://www.ncbi.nlm.nih.gov/pubmed/36291713
http://dx.doi.org/10.3390/biom12101504