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High-Resolution Ribosome Profiling Reveals Gene-Specific Details of UGA Re-Coding in Selenoprotein Biosynthesis
Co-translational incorporation of selenocysteine (Sec) into selenoproteins occurs at UGA codons in a process in which translational elongation competes with translational termination. Selenocysteine insertion sequence-binding protein 2 (SECISBP2) greatly enhances Sec incorporation into selenoprotein...
Autores principales: | Bohleber, Simon, Fradejas-Villar, Noelia, Zhao, Wenchao, Reuter, Uschi, Schweizer, Ulrich |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599142/ https://www.ncbi.nlm.nih.gov/pubmed/36291713 http://dx.doi.org/10.3390/biom12101504 |
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