PTEN Protein Phosphatase Activity Is Not Required for Tumour Suppression in the Mouse Prostate

Loss PTEN function is one of the most common events driving aggressive prostate cancers and biochemically, PTEN is a lipid phosphatase which opposes the activation of the oncogenic PI3K-AKT signalling network. However, PTEN also has additional potential mechanisms of action, including protein phosph...

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Detalles Bibliográficos
Autores principales: Wise, Helen M., Harris, Adam, Kriplani, Nisha, Schofield, Adam, Caldwell, Helen, Arends, Mark J., Overton, Ian M., Leslie, Nick R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599176/
https://www.ncbi.nlm.nih.gov/pubmed/36291720
http://dx.doi.org/10.3390/biom12101511

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599176/
https://www.ncbi.nlm.nih.gov/pubmed/36291720
http://dx.doi.org/10.3390/biom12101511

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