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Identification of the O-Glycan Epitope Targeted by the Anti-Human Carcinoma Monoclonal Antibody (mAb) NEO-201

SIMPLE SUMMARY: Glycosylation is an important post-translational modification made on mammalian proteins and lipids. In cancer cells, the disruption of several glycosylation patterns, such as the O-glycosylation, has been observed. The expression of incomplete/truncated O-glycans in cancer cells occ...

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Detalles Bibliográficos
Autores principales: Tsang, Kwong Y., Fantini, Massimo, Zaki, Anjum, Mavroukakis, Sharon A., Morelli, Maria Pia, Annunziata, Christina M., Arlen, Philip M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599200/
https://www.ncbi.nlm.nih.gov/pubmed/36291783
http://dx.doi.org/10.3390/cancers14204999