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The Epigenetic Dimension of Protein Structure Is an Intrinsic Weakness of the AlphaFold Program
One of the most important lessons we have learned from sequencing the human genome is that not all proteins have a 3D structure. In fact, a large part of the human proteome is made up of intrinsically disordered proteins (IDPs) which can adopt multiple structures, and therefore, multiple functions,...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599222/ https://www.ncbi.nlm.nih.gov/pubmed/36291736 http://dx.doi.org/10.3390/biom12101527 |