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Exosomal miR92a Promotes Cytarabine Resistance in Myelodysplastic Syndromes by Activating Wnt/β-catenin Signal Pathway

Cytarabine (Ara-C) has been one of the frontline therapies for clonal hematopoietic stem cell disorders, such as myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML), but Ara-C resistance often occurs and leads to treatment failure. Exosomal microRNAs (miRNAs, miRs) as small noncoding RNA...

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Detalles Bibliográficos
Autores principales: Li, Hongjiao, Xie, Chenglian, Lu, Yurong, Chang, Kaijing, Guan, Feng, Li, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599242/
https://www.ncbi.nlm.nih.gov/pubmed/36291656
http://dx.doi.org/10.3390/biom12101448