Multiple Sclerosis: Enzymatic Cross Site-Specific Recognition and Hydrolysis of H3 Histone by IgGs against H3, H1, H2A, H2B, H4 Histones, Myelin Basic Protein, and DNA

Histones have a specific key role in the remodeling of chromatin and gene transcription. In the blood, free histones are damage-connected proteins. Myelin basic protein (MBP) is the major component of the myelin-proteolipid sheath of axons. Antibodies possessing enzymatic activities (abzymes, ABZs)...

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Detalles Bibliográficos
Autores principales: Nevinsky, Georgy A., Buneva, Valentina N., Dmitrenok, Pavel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599260/
https://www.ncbi.nlm.nih.gov/pubmed/36289924
http://dx.doi.org/10.3390/biomedicines10102663

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599260/
https://www.ncbi.nlm.nih.gov/pubmed/36289924
http://dx.doi.org/10.3390/biomedicines10102663

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