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The Combined Escherichia coli Nissle 1917 and Tryptophan Treatment Modulates Immune and Metabolome Responses to Human Rotavirus Infection in a Human Infant Fecal Microbiota-Transplanted Malnourished Gnotobiotic Pig Model

Human rotavirus (HRV) is a major cause of childhood diarrhea in developing countries where widespread malnutrition contributes to the decreased oral vaccine efficacy and increased prevalence of other enteric infections, which are major concerns for global health. Neonatal gnotobiotic (Gn) piglets cl...

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Detalles Bibliográficos
Autores principales: Michael, Husheem, Srivastava, Vishal, Deblais, Loic, Amimo, Joshua O., Chepngeno, Juliet, Saif, Linda J., Rajashekara, Gireesh, Vlasova, Anastasia N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599269/
https://www.ncbi.nlm.nih.gov/pubmed/36073800
http://dx.doi.org/10.1128/msphere.00270-22