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Deciphering the Alphabet of Disorder—Glu and Asp Act Differently on Local but Not Global Properties

Compared to folded proteins, the sequences of intrinsically disordered proteins (IDPs) are enriched in polar and charged amino acids. Glutamate is one of the most enriched amino acids in IDPs, while the chemically similar amino acid aspartate is less enriched. So far, the underlying functional diffe...

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Detalles Bibliográficos
Autores principales: Roesgaard, Mette Ahrensback, Lundsgaard, Jeppe E., Newcombe, Estella A., Jacobsen, Nina L., Pesce, Francesco, Tranchant, Emil E., Lindemose, Søren, Prestel, Andreas, Hartmann-Petersen, Rasmus, Lindorff-Larsen, Kresten, Kragelund, Birthe B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599281/
https://www.ncbi.nlm.nih.gov/pubmed/36291634
http://dx.doi.org/10.3390/biom12101426