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Deciphering the Alphabet of Disorder—Glu and Asp Act Differently on Local but Not Global Properties
Compared to folded proteins, the sequences of intrinsically disordered proteins (IDPs) are enriched in polar and charged amino acids. Glutamate is one of the most enriched amino acids in IDPs, while the chemically similar amino acid aspartate is less enriched. So far, the underlying functional diffe...
Autores principales: | Roesgaard, Mette Ahrensback, Lundsgaard, Jeppe E., Newcombe, Estella A., Jacobsen, Nina L., Pesce, Francesco, Tranchant, Emil E., Lindemose, Søren, Prestel, Andreas, Hartmann-Petersen, Rasmus, Lindorff-Larsen, Kresten, Kragelund, Birthe B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599281/ https://www.ncbi.nlm.nih.gov/pubmed/36291634 http://dx.doi.org/10.3390/biom12101426 |
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