Sensitization of Patient-Derived Colorectal Cancer Organoids to Photon and Proton Radiation by Targeting DNA Damage Response Mechanisms

SIMPLE SUMMARY: Radiotherapy plays an important role in the treatment of colorectal cancer (CRC). Approximately one-third of patients with rectal cancer show a pathological complete response upon total neoadjuvant treatment. Patient-derived CRC organoids were investigated regarding their radiotherap...

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Detalles Bibliográficos
Autores principales: Pape, Kristin, Lößner, Anna J., William, Doreen, Czempiel, Tabea, Beyreuther, Elke, Klimova, Anna, Lehmann, Claudia, Schmäche, Tim, Merker, Sebastian R., Naumann, Max, Ada, Anne-Marlen, Baenke, Franziska, Seidlitz, Therese, Bütof, Rebecca, Dietrich, Antje, Krause, Mechthild, Weitz, Jürgen, Klink, Barbara, von Neubeck, Cläre, Stange, Daniel E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599341/
https://www.ncbi.nlm.nih.gov/pubmed/36291768
http://dx.doi.org/10.3390/cancers14204984

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599341/
https://www.ncbi.nlm.nih.gov/pubmed/36291768
http://dx.doi.org/10.3390/cancers14204984

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