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Characterizing the Contributions of Various Clostridium perfringens Enterotoxin Properties to In Vivo and In Vitro Permeability Effects

Clostridium perfringens enterotoxin (CPE) is thought to cause lethal enterotoxemia when absorbed from the intestinal lumen into the circulation. CPE action sequentially involves receptor-binding, oligomerization into a prepore, and pore formation. To explore the mechanistic basis by which CPE alters...

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Detalles Bibliográficos
Autores principales: Shrestha, Archana, Navarro, Mauricio A., Beingesser, Juliann, Armien, Anibal G., Uzal, Francisco A., McClane, Bruce A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599344/
https://www.ncbi.nlm.nih.gov/pubmed/36069435
http://dx.doi.org/10.1128/msphere.00276-22