c-Myc Sustains Pancreatic Cancer Cell Survival and mutp53 Stability through the Mevalonate Pathway

It has been shown that wild-type (wt)p53 inhibits oncogene c-Myc while mutant (mut)p53 may transactivate it, with an opposite behavior that frequently occurs in the crosstalk of wt or mutp53 with molecules/pathways promoting carcinogenesis. Even if it has been reported that mutp53 sustains c-Myc, wh...

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Detalles Bibliográficos
Autores principales: Romeo, Maria Anele, Gilardini Montani, Maria Saveria, Arena, Andrea, Benedetti, Rossella, D’Orazi, Gabriella, Cirone, Mara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599358/
https://www.ncbi.nlm.nih.gov/pubmed/36289751
http://dx.doi.org/10.3390/biomedicines10102489

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599358/
https://www.ncbi.nlm.nih.gov/pubmed/36289751
http://dx.doi.org/10.3390/biomedicines10102489

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