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Perturbations of mesenchymal stromal cells after allogeneic hematopoietic cell transplantation predispose for bone marrow graft-versus-host-disease

Functional impairment of the bone marrow (BM) niche has been suggested as a major reason for prolonged cytopenia and secondary graft failure after allogeneic hematopoietic cell transplantation (alloHCT). Because mesenchymal stromal cells (MSCs) serve as multipotent progenitors for several niche comp...

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Detalles Bibliográficos
Autores principales: Krüger, Thomas, Wehner, Rebekka, Herbig, Maik, Kräter, Martin, Kramer, Michael, Middeke, Jan Moritz, Stölzel, Friedrich, List, Catrin, Egger-Heidrich, Katharina, Teipel, Raphael, Oelschlägel, Uta, Wermke, Martin, Jambor, Helena, Wobus, Manja, Schetelig, Johannes, Jöhrens, Korinna, Tonn, Torsten, Subburayalu, Julien, Schmitz, Marc, Bornhauser, Martin, von Bonin, Malte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599394/
https://www.ncbi.nlm.nih.gov/pubmed/36311725
http://dx.doi.org/10.3389/fimmu.2022.1005554