Sequential Deletions of Interferon Inhibitors MGF110-9L and MGF505-7R Result in Sterile Immunity against the Eurasia Strain of Africa Swine Fever

African swine fever virus (ASFV) causes significant morbidity and mortality in pigs worldwide. The lack of vaccines or therapeutic options warrants urgent further investigation. To this aim, we developed a rationally designed live attenuated ASFV-Δ110-9L/505-7R mutant based on the highly pathogenic...

Descripción completa

Detalles Bibliográficos
Autores principales: Ding, Mingyang, Dang, Wen, Liu, Huanan, Zhang, Keshan, Xu, Fan, Tian, Hong, Huang, Huaguo, Shi, Zhengwang, Sunkang, Yongjie, Qin, Xiaodong, Zhang, Yong, Zheng, Haixue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Vaccines and Antiviral Agents
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599437/
https://www.ncbi.nlm.nih.gov/pubmed/36197109
http://dx.doi.org/10.1128/jvi.01192-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599437/
https://www.ncbi.nlm.nih.gov/pubmed/36197109
http://dx.doi.org/10.1128/jvi.01192-22

Ejemplares similares