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Sequential Deletions of Interferon Inhibitors MGF110-9L and MGF505-7R Result in Sterile Immunity against the Eurasia Strain of Africa Swine Fever
African swine fever virus (ASFV) causes significant morbidity and mortality in pigs worldwide. The lack of vaccines or therapeutic options warrants urgent further investigation. To this aim, we developed a rationally designed live attenuated ASFV-Δ110-9L/505-7R mutant based on the highly pathogenic...
Autores principales: | Ding, Mingyang, Dang, Wen, Liu, Huanan, Zhang, Keshan, Xu, Fan, Tian, Hong, Huang, Huaguo, Shi, Zhengwang, Sunkang, Yongjie, Qin, Xiaodong, Zhang, Yong, Zheng, Haixue |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599437/ https://www.ncbi.nlm.nih.gov/pubmed/36197109 http://dx.doi.org/10.1128/jvi.01192-22 |
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