The Tumor Suppressor Protein TRAF3 Modulates GSK3 Activity and Susceptibility of B Lymphoma Cells to GSK3 Inhibition

SIMPLE SUMMARY: TRAF3 is an adapter protein that regulates signals through many receptors important for B cell differentiation and function. Loss-of-function mutations or deletions of TRAF3 are common in B cell malignancies. Glycogen Synthase Kinase 3 (GSK3) regulates signaling in growth, survival,...

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Detalles Bibliográficos
Autores principales: Hornick, Emma L., Stunz, Laura L., Sabree, Shakoora, Wu, Xiaosheng, Witzig, Thomas E., Bishop, Gail A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599470/
https://www.ncbi.nlm.nih.gov/pubmed/36291813
http://dx.doi.org/10.3390/cancers14205029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599470/
https://www.ncbi.nlm.nih.gov/pubmed/36291813
http://dx.doi.org/10.3390/cancers14205029

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