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The Tumor Suppressor Protein TRAF3 Modulates GSK3 Activity and Susceptibility of B Lymphoma Cells to GSK3 Inhibition
SIMPLE SUMMARY: TRAF3 is an adapter protein that regulates signals through many receptors important for B cell differentiation and function. Loss-of-function mutations or deletions of TRAF3 are common in B cell malignancies. Glycogen Synthase Kinase 3 (GSK3) regulates signaling in growth, survival,...
Autores principales: | Hornick, Emma L., Stunz, Laura L., Sabree, Shakoora, Wu, Xiaosheng, Witzig, Thomas E., Bishop, Gail A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599470/ https://www.ncbi.nlm.nih.gov/pubmed/36291813 http://dx.doi.org/10.3390/cancers14205029 |
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