Human Melanocortin-2 Receptor: Identifying a Role for Residues in the TM4, EC2, and TM5 Domains in Activation and Trafficking as a Result of Co-Expression with the Accessory Protein, Mrap1 in Chinese Hamster Ovary Cells

Human melanocortin-2 receptor (hMC2R) co-expressed with the accessory protein mouse (m)MRAP1 in Chinese Hamster Ovary (CHO) cells has been used as a model system to investigate the activation and trafficking of hMC2R. A previous study had shown that the N-terminal domain of mMRAP1 makes contact with...

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Detalles Bibliográficos
Autores principales: Davis, Perry V., Shaughnessy, Ciaran A., Dores, Robert M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599514/
https://www.ncbi.nlm.nih.gov/pubmed/36291631
http://dx.doi.org/10.3390/biom12101422

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599514/
https://www.ncbi.nlm.nih.gov/pubmed/36291631
http://dx.doi.org/10.3390/biom12101422

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