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A Candidate Therapeutic Monoclonal Antibody Inhibits Both HRSV and HMPV Replication in Mice

Human metapneumovirus (HMPV) and human respiratory virus (HRSV) are two leading causes of acute respiratory tract infection in young children. While there is no licensed drug against HMPV, the monoclonal antibody (mAb) Palivizumab is approved against HRSV for prophylaxis use only. Novel therapeutics...

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Detalles Bibliográficos
Autores principales: Fausther-Bovendo, Hugues, Hamelin, Marie-Eve, Carbonneau, Julie, Venable, Marie-Christine, Checkmahomed, Liva, Lavoie, Pierre-Olivier, Ouellet, Marie-Ève, Boivin, Guy, D’Aoust, Marc-André, Kobinger, Gary P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599547/
https://www.ncbi.nlm.nih.gov/pubmed/36289776
http://dx.doi.org/10.3390/biomedicines10102516