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Nef Suppresses LINE-1 Retrotransposition through Two Distinct Mechanisms
Long interspersed element type 1 (LINE-1) is the only known type of retroelement that can replicate autonomously, and its retrotransposition activity can trigger interferon (IFN) production. IFN production suppresses the infectivity of exogenous viruses, such as human immunodeficiency virus (HIV). A...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599549/ https://www.ncbi.nlm.nih.gov/pubmed/36197106 http://dx.doi.org/10.1128/jvi.01148-22 |