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Nef Suppresses LINE-1 Retrotransposition through Two Distinct Mechanisms

Long interspersed element type 1 (LINE-1) is the only known type of retroelement that can replicate autonomously, and its retrotransposition activity can trigger interferon (IFN) production. IFN production suppresses the infectivity of exogenous viruses, such as human immunodeficiency virus (HIV). A...

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Detalles Bibliográficos
Autores principales:	Wang, Yu, Zhao, Ke, Zhao, Yifei, Zhao, Zihan, Wang, Shaohua, Du, Juan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2022
Materias:	Virus-Cell Interactions
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599549/ https://www.ncbi.nlm.nih.gov/pubmed/36197106 http://dx.doi.org/10.1128/jvi.01148-22

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