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A Trade-Off for Maintenance of Multidrug-Resistant IncHI2 Plasmids in Salmonella enterica Serovar Typhimurium through Adaptive Evolution

Understanding the fitness costs associated with plasmid carriage is a key to better understanding the mechanisms of plasmid maintenance in bacteria. In the current work, we performed multiple serial passages (63 days, 627.8 generations) to identify the compensatory mechanisms that Salmonella enteric...

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Detalles Bibliográficos
Autores principales: Zhang, Jin-Fei, Fang, Liang-Xing, Chang, Man-Xia, Cheng, Ming, Zhang, Hui, Long, Teng-Fei, Li, Qian, Lian, Xin-lei, Sun, Jian, Liao, Xiao-Ping, Liu, Ya-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599605/
https://www.ncbi.nlm.nih.gov/pubmed/36040022
http://dx.doi.org/10.1128/msystems.00248-22