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Zebrafish Model of Severe Combined Immunodeficiency (SCID) Due to JAK3 Mutation
JAK3 is principally activated by members of the interleukin-2 receptor family and plays an essential role in lymphoid development, with inactivating JAK3 mutations causing autosomal-recessive severe combined immunodeficiency (SCID). This study aimed to generate an equivalent zebrafish model of SCID...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599616/ https://www.ncbi.nlm.nih.gov/pubmed/36291730 http://dx.doi.org/10.3390/biom12101521 |